Nicotinamide Riboside (NR) is a recently discovered form of vitamin B3 that can increase levels of Nicotinamide Adenine Dinucleotide (NAD+). NAD+ is a key co-enzyme used by the mitochondria in every cell of our bodies. With natural ageing or disease or chronic inflammation NAD+ levels drop. The hope is that by supplementing NR we can in turn increase NAD+, and make muscles, organs and tissues perform closer to younger versions of themselves.

Rhonda talked about this supplement in the Tim Ferriss podcast titled “Exploring Smart Drugs, Fasting, and Fat Loss”. Where she said (transcript source):

I mix in some other supplements like the meriva formulation of curcumin, which I already talked about earlier, and I am just starting to mix in a little nicotinamide riboside into the mix.

I’m afraid that the supplement I’m taking right now, which is by Thorne and only has 125 mg per capsule, won’t quite cut it to meet some of the robust results being seen in animal studies. I think there is potential here but more studies in humans definitely need to be done at this point. Still interested though.

Rhonda uses Thorne’s NiaCel, which contains 125mg of nicotinamide riboside chloride as the only ingredient.

Thorne have also introduced a double strength version to the market – Niacel-250.

Since she got pregnant Rhonda actually stopped taking any non-essential supplements (including Nicotinamide Riboside) that could pose even the slightest risk to her child. But she has said in her March Patreon Q&A that she will carry on experimenting with nicotinamide riboside once she finishes breastfeeding.

For more information on all Rhonda’s supplements, see: Dr Rhonda Patrick’s Supplements List – 2018 Update


Posted by Alex

One Comment

  1. Avatar
    Ignatius Turchi August 2, 2018 at 3:32 pm

    A company called “Alive by Nature” discusses the greater bioavailability of NMN relative to NR on their website. They also sell NMN. I’ve decided to take both NR (500 mg) and NMN sublingual (500 mg). I am still up in the air about this.


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