Multivitamins provide a blend of essential micronutrients—vitamins and minerals—deemed vital because their absence causes illness in experiments. Humans require over 40 such nutrients for health, sourced mainly from diet. Research by Bruce Ames shows that insufficient levels prompt the body to allocate scarce resources to survival and reproduction, sidelining functions like longevity support. Supplements aim to fill gaps, potentially enhancing overall wellness.

Influencers who take one and which type:
| Influencer | Product |
| Rhonda Patrick | Pure Encapsulations ONE |
| Andrew Huberman | Optimum Nutrition Opti-Men |
| Kevin Rose | MegaFood Advanced |