This post covers the changes I’ve made to the Rhonda Patrick Supplements article over time.
April 13, 2021 – Updated:
- The new US alternative to Prostaphane, called Broq, now has a link from the Prostaphane.com website – confirming that it’s made by them. On Rhonda’s previous Q&A she noted that it *should* be the same, but hadn’t yet looked into it. I’ve updated the post to include this connection between Prostaphane and Broq.
Feb 22, 2021 – Updated:
- Off the back of Rhonda’s Feb Q&A update, brought Rhonda’s list of supplements up to date. Noteably, added ubiquinone, and adjusted some of the doses. Her focus on “immune support” supplements from March 2020 was (understandably) reduced, with vitamin C and Quercetin sticking around, and NAC + liposomal glutathione being removed.
Feb 1, 2021 – Updated:
- Large reshuffle of the post to bring certain aspects more up to date and make other aspects clearer. For example, there are many comments that say something like “that’s a huge amount of supplements, I don’t know where to start” – therefore I sub-divided by “core” supplements, supplements Rhonda mentioned for immune function, then additional supplements she takes regularly.
- Adjusted Joe Rogan YouTube links (no longer available) over to Spotify links.
- Moved bulk sulforaphane content into a separate post to simply things.
Nov 2, 2020 – Updated:
- Back when the pandemic started this year, Rhonda switched up her supplement regime to provide maximal immune function. Part of that involved taking a probiotic daily (Visbiome). Updated to reflect that she’s now gone back to taking it once every 1-2 weeks as a top up.
July 10, 2020 – Updated:
- Updated the section on K2 to better reflect my understanding (via Rhonda) of the interplay between K1 and K2, and thus the reason for interest in occasional K2 supplementation.
June 14, 2020 – Updated:
- Rhonda discussed her cocoa supplementation in more detail in her May crowdcast, and have updated that section with the new info.
May 19, 2020 – Updated:
Rhonda mentioned a couple of new things in her recent appearance on the Joe Rogan experience (#1474) podcast:
- Switched from vitamin K2 MK7 (used previously) to MK4 form.
- Increased her nightly dose of melatonin to 9mg – which has all but stopped her night terrors.
April 26, 2020 – Updated:
Added mention of:
- Buckwheat tea for it’s quercetin content
- Moringa as a NRF2 activator, similar to sulforaphane
April 13, 2020 – Updated:
- In light of the recent pandemic, Rhonda has adjusted her daily supplements in order to provide additional immune support. Including:
- More reliance on her multivitamin, whilst she has less access to fresh vegetables
- A slight increase in vitamin D dosage, and emphasis on its importance
- High dose supplementation of vitamin C, taken regularly throughout the day
- Adding additional zinc
- Adding quercetin, for its potential ability to increase zinc absorption
- The addition of N-acetyl L-cysteine and liposomal glutathione
- Moving to daily use of visbiome probiotic sachets
March 7, 2020 – Updated:
- Based on one of Rhonda’s recent Crowdcasts, I think I jumped the gun on linking Rhonda’s concern over lead picolate being added to turmeric, and her discontinuation of taking a curcumin supplement daily (Thorne Meriva). She still appears enthusiastic about its use for mild pain relief, and as such have corrected the post to reflect that.
Jan 8, 2020 – Updated:
- Based on the recent podcast with Kevin Rose (Jan 2020 – link), I’ve updated Rhonda’s preferred magnesium supplement to Thorne’s Magnesium Bisglycinate, and noted that she takes it occasionally, preferring to get magnesium from her diet – in particular leafy greens.
- Added section on metformin, noting her thoughts on its use for healthspan/lifespan extension.
- Added alternative options to the Activz beet powder, because it appears to be sold out everywhere
December 10, 2019 – Updated:
- This update is a major overhaul to the post, after Rhonda’s latest CrowdCast discussed changes to her supplement regime.
- Changes of note include:
- A change to the Vitamin K2 brand she is using; now Life Extension Low-Dose Vitamin K2 (MK-7)
- Use of PQQ as a daily supplement – similar to when she was breastfeeding.
- The addition of a high cocoa flavanol supplement – CocoaVia
- Using a sulforaphane supplement daily, while she doesn’t have time to grow her own broccoli sprouts
- Adding low dose melatonin supplement in the evenings
- Switching from taking the high DHA omega-3 supplement, to taking 50% high DHA and 50% high EPA.
- Rhonda appears to be no longer using supplements like curcumin, Lion’s Mane and Nicotinamide Riboside, all of which she was using previously. Rather than scrub them from the list, I’ve added a section at the bottom of the main post which explains why (given the information available) she has stopped taking them.
September 17, 2019 – Updated:
- Added section on melatonin, which Rhonda has discussed as useful for those 50+, whose natural production has decreased, and for those with trouble sleeping. With specific reference to the MIT study she cites on dose quantity.
September 4, 2019 – Updated:
- Added note to nicotinamide riboside section regarding discontinuation of Thorne’s Niacel, noting that the core ingredient Thorne used was Chromadex’s, and that can still be purchased via Chromadex’s own brand product; Niagen.
March 6, 2019 – Updated:
- Added note on broccoli sprout seeds, based on discussion in the comments. Noting that some broccoli seed retailers are selling “Rapini/Raab/Rabe” seeds, under the guise of broccoli seeds. When for our purposes, they are of a different brassica family – despite looking visually similar to broccoli. This is important because we do not know if Rapini contain sulforaphane.
January 28, 2019 – Updated:
- Updated probiotics section with information regarding the VSL #3 vs Visbiome lawsuit. The relevant part is that VSL #3 (which Rhonda used to take), changed formulas in 2016, and the current formula is materially different to the version that was the subject of 25+ studies showing efficacy. This means that a) people should be cautious if using VSL#3 as a substitute for Visbiome (which uses the original formula), and b) the previous VSL#3 studies would need to be re-done.
- Various miscellaneous tweaks, including updating images and re-phrasing certain sections.
January 8, 2019 – Updated:
- Added content to curcumin section on double-blind randomized placebo-controlled trial showing antidepressive effects in patients with major depression.
November 25, 2018 – Updated:
- Added section to fish oils regarding APOE4, alzheimer’s & omega-3 phospholipids.
- Updated sulforaphane section based on August 2018 CrowdCast – Rhonda now harvests broccoli sprouts every 3 days, whilst they are still young, and opts to store them in the fridge rather than freeze them. She also no longer follows or recommends the heating/steeping process to increase bioavailability.
- Updated section on Lion’s Mane regarding heavy metals
August 17, 2018 – Updated:
- Rhonda’s K2 supplement choice from NOW Vitamin’s K2-MK7 to Thorne Research’s – K2/D3 liquid drops. Hat tip to Jim, who provided this info in the comments.
- It seems that around 9 months ago, since Rhonda explained the details of her supplement choices on Tim Ferriss’ May 2017 podcast, she has switched her brand choice of K2 over to Thorne’s liquid form K2 MK4. However she has kept using the same dosage (100mcg), which with Thorne is 1 drop. The source for this can be found on her site here. The switch to Thorne could be spurred by some of Dr Jed Fahey’s sulforaphane research. He found when testing brands that Thorne contained what they said, whereas many other brands he tested did not.
August 16, 2018 & Prior
- Updates were being made, but I wasn’t logging them yet.